Publications

Epivolve

Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326)

Mary R. Ferguson, Kristina N. Delgado, Shannon McBride, Isabel C. Orbe, Carson J. La Vake, Melissa J. Caimano, Qiana Mendez, Trevor F. Moraes, Anthony B. Schryvers, M. Anthony Moody, Justin D. Radolf, Michael P. Weiner and Kelly L. Hawley

Epivolve

Site-directed neutralizing antibodies targeting structural sites on SARS-CoV-2 spike protein

Xiaofeng Li, Liudmila Kulakova, Kezzia Jones, Eric A. Toth, Marina Kirkland Mitchell, Qiana Mendez, Michael P. Weiner, Thomas R. Fuerst

Epivolve

Derivation of splice junction-specific antibodies using a unique hapten targeting strategy and directed evolution

Emily P Fuller, Rachel J O’Neill, Michael P Weiner

Additional Technologies

Rational library design by functional CDR resampling

Qi Zhao, Diane Buhr, Courtney Gunter, Jenny Frenette, Mary Ferguson, Eric Sanford, Erika Holland, Chitra Rajagopal, Melissa Batonick, Margaret M Kiss, Michael P Weiner

Additional Technologies

MILKSHAKE Western blot and Sundae ELISA: We all scream for better antibody validation

Qiana Mendez, Holland A Driscoll, Gregory R Mirando, Felicity Acca, Cassandra D Chapados, Kezzia S Jones, Michael Weiner, Xiaofeng Li, Mary R Ferguson

Additional Technologies

AXM mutagenesis: an efficient means for the production of libraries for directed evolution of proteins.

Holland EG, Buhr DL, Acca FE, Alderman D, Bovat K, Busygina V, Kay BK, Weiner MP, Kiss MM.

Additional Technologies

pMINERVA: A donor-acceptor system for the in vivo recombineering of scFv into IgG molecules.

Batonick M, Kiss MM, Fuller EP, Magadan CM, Holland EG, Zhao Q, Wang D, Kay BK, Weiner MP